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SP1 Antikörper (C-Term)

Der Kaninchen Polyklonal Anti-SP1-Antikörper wurde für WB, IF, IHC (p) und ICC validiert. Er ist geeignet, SP1 in Proben von Human zu detektieren.
Produktnummer ABIN2855540

Kurzübersicht für SP1 Antikörper (C-Term) (ABIN2855540)

Target

Alle SP1 Antikörper anzeigen
SP1 (Sp1 Transcription Factor (SP1))

Reaktivität

  • 90
  • 59
  • 38
  • 11
  • 8
  • 7
  • 7
  • 6
  • 5
  • 5
  • 4
  • 2
  • 2
  • 2
  • 1
Human

Wirt

  • 93
  • 14
  • 3
Kaninchen

Klonalität

  • 85
  • 25
Polyklonal

Konjugat

  • 76
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser SP1 Antikörper ist unkonjugiert

Applikation

  • 95
  • 48
  • 47
  • 42
  • 20
  • 19
  • 14
  • 13
  • 13
  • 13
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
  • Bindungsspezifität

    • 21
    • 12
    • 10
    • 7
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    Kreuzreaktivität

    Human

    Produktmerkmale

    Rabbit Polyclonal antibody to SP1 (Sp1 transcription factor)
    SP1 antibody

    Aufreinigung

    Purified by antigen-affinity chromatography.

    Immunogen

    Recombinant protein encompassing a sequence within the C-terminus region of human SP1. The exact sequence is proprietary.

    Isotyp

    IgG
  • Applikationshinweise

    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    Kommentare

    Positive Control: THP-1

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 mg/mL

    Buffer

    1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal

    Konservierungsmittel

    Thimerosal (Merthiolate)

    Vorsichtsmaßnahmen

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target

    SP1 (Sp1 Transcription Factor (SP1))

    Andere Bezeichnung

    Sp1 transcription factor

    Hintergrund

    Transcription factor that can activate or repress transcription in response to physiological and pathological stimuli. Binds with high affinity to GC-rich motifs and regulates the expression of a large number of genes involved in a variety of processes such as cell growth, apoptosis, differentiation and immune responses. Highly regulated by post-translational modifications (phosphorylations, sumoylation, proteolytic cleavage, glycosylation and acetylation). Binds also the PDGFR-alpha G-box promoter. May have a role in modulating the cellular response to DNA damage. Implicated in chromatin remodeling. Plays a role in the recruitment of SMARCA4/BRG1 on the c-FOS promoter. Plays an essential role in the regulation of FE65 gene expression.

    Cellular Localization: Nucleus

    Molekulargewicht

    81 kDa

    Gen-ID

    6667

    UniProt

    P08047

    Pathways

    Regulation of Lipid Metabolism by PPARalpha, Myometrial Relaxation and Contraction
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