NNT Antikörper (C-Term)
Kurzübersicht für NNT Antikörper (C-Term) (ABIN2855538)
Target
Alle NNT Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Güteklasse
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Bindungsspezifität
- C-Term
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Kreuzreaktivität
- Human, Maus, Ratte
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Produktmerkmale
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Rabbit Polyclonal antibody to NNT (nicotinamide nucleotide transhydrogenase)
NNT antibody -
Aufreinigung
- Purified by antigen-affinity chromatography.
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Immunogen
- Recombinant protein encompassing a sequence within the C-terminus region of human NNT. The exact sequence is proprietary.
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Isotyp
- IgG
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Applikationshinweise
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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Kommentare
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Positive Control: rat kidney , 293T
Validation: KO/KD
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.23 mg/mL
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Buffer
- 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- NNT (Nicotinamide Nucleotide Transhydrogenase (NNT))
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Andere Bezeichnung
- nicotinamide nucleotide transhydrogenase
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Hintergrund
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This gene encodes an integral protein of the inner mitochondrial membrane. The enzyme couples hydride transfer between NAD(H) and NADP(+) to proton translocation across the inner mitochondrial membrane. Under most physiological conditions, the enzyme uses energy from the mitochondrial proton gradient to produce high concentrations of NADPH. The resulting NADPH is used for biosynthesis and in free radical detoxification. Two alternatively spliced variants, encoding the same protein, have been found for this gene.
Cellular Localization: Mitochondrion inner membrane, Multi-pass membrane protein, Matrix side -
Molekulargewicht
- 114 kDa
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Gen-ID
- 23530
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UniProt
- Q13423
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Pathways
- Proton Transport
Target
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