MIA3 Antikörper (N-Term)

Produktnummer ABIN2855189

Der Kaninchen Polyklonal Anti-MIA3-Antikörper wurde für WB, IHC (p), ICC und IF validiert. Er ist geeignet, MIA3 in Proben von Human zu detektieren.

Kurzübersicht für MIA3 Antikörper (N-Term) (ABIN2855189)

Target: MIA3 (Melanoma Inhibitory Activity Family, Member 3 (MIA3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MIA3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (IF)

Produktdetails anti-MIA3 Antikörper

Bindungsspezifität: N-Term

Kreuzreaktivität: Rind (Kuh)

Kreuzreaktivität (Details): Bovine (89 %)

Produktmerkmale: Rabbit Polyclonal antibody to MIA3 (melanoma inhibitory activity family, member 3)
MIA3 antibody [N1], N-term

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the N-terminus region of human MIA3. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 10 μg/mL* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)10 μg/mL* Western blot1:500-1:3000*

Kommentare:

Positive Control: A549 , HepG2

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.30 mg/mL

Buffer: 1XPBS, 1 % BSA, 20 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu MIA3

Target: MIA3 (Melanoma Inhibitory Activity Family, Member 3 (MIA3))

Andere Bezeichnung: MIA3

Hintergrund: Required for collagen VII (COL7A1) secretion by loading COL7A1 into transport carriers. May participate in cargo loading of COL7A1 at endoplasmic reticulum exit sites by binding to COPII coat subunits Sec23/24 and guiding SH3-bound COL7A1 into a growing carrier. Does not play a role in global protein secretion and is apparently specific to COL7A1 cargo loading. However, it may participate in secretion of other proteins in cells that do not secrete COL7A1.

Cellular Localization: Endoplasmic reticulum membrane, Single-pass type I membrane protein

Molekulargewicht: 214 kDa

Gen-ID: 375056