ACE2 Antikörper (N-Term)
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- Target Alle ACE2 Antikörper anzeigen
- ACE2 (Angiotensin I Converting Enzyme 2 (ACE2))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser ACE2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunofluorescence (IF)
- Kreuzreaktivität
- Green Monkey, Human, Maus, Ratte
- Produktmerkmale
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Rabbit Polyclonal antibody to ACE2 (angiotensin I converting enzyme (peptidyl-dipeptidase A) 2)
ACE2 antibody [N1N2], N-term - Aufreinigung
- Purified by antigen-affinity chromatography.
- Güteklasse
- KO Validated
- Immunogen
- Recombinant protein encompassing a sequence within the N-terminus region of human ACE2. The exact sequence is proprietary.
- Isotyp
- IgG
- Top Product
- Discover our top product ACE2 Primärantikörper
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- Applikationshinweise
- WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- Kommentare
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Validation: KO/KD, Orthogonal, Overexpression
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.2 mg/mL
- Buffer
- 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Target
- ACE2 (Angiotensin I Converting Enzyme 2 (ACE2))
- Andere Bezeichnung
- angiotensin I converting enzyme 2 (ACE2 Produkte)
- Synonyme
- ACE1 antikoerper, CD143 antikoerper, DCP antikoerper, DCP1 antikoerper, ICH antikoerper, MVCD3 antikoerper, ACEH antikoerper, 2010305L05Rik antikoerper, zgc:92514 antikoerper, angiotensin I converting enzyme antikoerper, angiotensin I converting enzyme 2 antikoerper, angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 antikoerper, ACE antikoerper, ACE2 antikoerper, Ace2 antikoerper, ace2 antikoerper
- Hintergrund
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The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63.
Cellular Localization: Processed angiotensin-converting enzyme 2: Secreted , Cell membrane - Molekulargewicht
- 92 kDa
- Gen-ID
- 59272
- UniProt
- Q9BYF1
- Pathways
- ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour
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