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ACE2 Antikörper (N-Term)

KO Validated ACE2 Reaktivität: Human WB, ELISA, IHC (p), FACS, ICC, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2855030
  • Target Alle ACE2 Antikörper anzeigen
    ACE2 (Angiotensin I Converting Enzyme 2 (ACE2))
    Bindungsspezifität
    • 16
    • 16
    • 14
    • 9
    • 9
    • 9
    • 9
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 149
    • 54
    • 47
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 136
    • 20
    • 6
    Kaninchen
    Klonalität
    • 116
    • 46
    Polyklonal
    Konjugat
    • 79
    • 18
    • 12
    • 8
    • 7
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ACE2 Antikörper ist unkonjugiert
    Applikation
    • 129
    • 75
    • 57
    • 35
    • 35
    • 19
    • 17
    • 11
    • 10
    • 10
    • 9
    • 6
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunofluorescence (IF)
    Kreuzreaktivität
    Green Monkey, Human, Maus, Ratte
    Produktmerkmale
    Rabbit Polyclonal antibody to ACE2 (angiotensin I converting enzyme (peptidyl-dipeptidase A) 2)
    ACE2 antibody [N1N2], N-term
    Aufreinigung
    Purified by antigen-affinity chromatography.
    Güteklasse
    KO Validated
    Immunogen
    Recombinant protein encompassing a sequence within the N-terminus region of human ACE2. The exact sequence is proprietary.
    Isotyp
    IgG
    Top Product
    Discover our top product ACE2 Primärantikörper
  • Applikationshinweise
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Kommentare

    Validation: KO/KD, Orthogonal, Overexpression

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.2 mg/mL
    Buffer
    1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    ACE2 (Angiotensin I Converting Enzyme 2 (ACE2))
    Andere Bezeichnung
    angiotensin I converting enzyme 2 (ACE2 Produkte)
    Synonyme
    ACE1 antikoerper, CD143 antikoerper, DCP antikoerper, DCP1 antikoerper, ICH antikoerper, MVCD3 antikoerper, ACEH antikoerper, 2010305L05Rik antikoerper, zgc:92514 antikoerper, angiotensin I converting enzyme antikoerper, angiotensin I converting enzyme 2 antikoerper, angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 antikoerper, ACE antikoerper, ACE2 antikoerper, Ace2 antikoerper, ace2 antikoerper
    Hintergrund
    The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63.

    Cellular Localization: Processed angiotensin-converting enzyme 2: Secreted , Cell membrane
    Molekulargewicht
    92 kDa
    Gen-ID
    59272
    UniProt
    Q9BYF1
    Pathways
    ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour
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