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BLM Antikörper (C-Term)

Der Kaninchen Polyklonal Anti-BLM-Antikörper wurde für WB, IF, IHC (p) und ICC validiert. Er ist geeignet, BLM in Proben von Human und Maus zu detektieren.
Produktnummer ABIN2855003

Kurzübersicht für BLM Antikörper (C-Term) (ABIN2855003)

Target

Alle BLM Antikörper anzeigen
BLM (Bloom Syndrome RecQ Like Helicase (BLM))

Reaktivität

  • 54
  • 7
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human, Maus

Wirt

  • 55
  • 3
  • 2
Kaninchen

Klonalität

  • 58
  • 2
Polyklonal

Konjugat

  • 32
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser BLM Antikörper ist unkonjugiert

Applikation

  • 41
  • 27
  • 13
  • 13
  • 12
  • 10
  • 9
  • 7
  • 6
  • 3
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
  • Bindungsspezifität

    • 15
    • 8
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    Produktmerkmale

    Rabbit Polyclonal antibody to BLM (Bloom syndrome, RecQ helicase-like)
    BLM antibody [C3], C-term

    Aufreinigung

    Purified by antigen-affinity chromatography.

    Immunogen

    Recombinant protein encompassing a sequence within the C-terminus region of human BLM. The exact sequence is proprietary.

    Isotyp

    IgG
  • Applikationshinweise

    Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*

    Kommentare

    Positive Control: Jurkat , Raji , K562 , NCI-H929 , NIH-3T3 , JC , BCL-1

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    0.35 mg/mL

    Buffer

    0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

    Konservierungsmittel

    Thimerosal (Merthiolate)

    Vorsichtsmaßnahmen

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target

    BLM (Bloom Syndrome RecQ Like Helicase (BLM))

    Andere Bezeichnung

    BLM

    Hintergrund

    The Bloom syndrome gene product is related to the RecQ subset of DExH box-containing DNA helicases and has both DNA-stimulated ATPase and ATP-dependent DNA helicase activities. Mutations causing Bloom syndrome delete or alter helicase motifs and may disable the 3'-5' helicase activity. The normal protein may act to suppress inappropriate recombination.

    Cellular Localization: Nucleus

    Molekulargewicht

    159 kDa

    Gen-ID

    641

    Pathways

    DNA Reparatur
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