DTNBP1 Antikörper
Kurzübersicht für DTNBP1 Antikörper (ABIN2854989)
Target
Alle DTNBP1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Kreuzreaktivität
- Human, Maus, Ratte
-
Produktmerkmale
-
Rabbit Polyclonal antibody to Dysbindin (dystrobrevin binding protein 1)
Dysbindin antibody -
Aufreinigung
- Purified by antigen-affinity chromatography.
-
Immunogen
- Recombinant protein encompassing a sequence within the center region of human Dysbindin. The exact sequence is proprietary.
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
-
Kommentare
-
Positive Control: NT2D1 , PC-3 , U87-MG , SK-N-SH , mouse brain , rat brain
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- 1 mg/mL
-
Buffer
- 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal
-
Konservierungsmittel
- Thimerosal (Merthiolate)
-
Vorsichtsmaßnahmen
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- 4 °C,-20 °C
-
Informationen zur Lagerung
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
-
-
- DTNBP1 (Dystrobrevin Binding Protein 1 (DTNBP1))
-
Andere Bezeichnung
- dystrobrevin binding protein 1
-
Hintergrund
-
This gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. A similar protein in mouse is a component of a protein complex termed biogenesis of lysosome-related organelles complex 1 (BLOC-1), and binds to alpha- and beta-dystrobrevins, which are components of the dystrophin-associated protein complex (DPC). Mutations in this gene are associated with Hermansky-Pudlak syndrome type 7. This gene may also be associated with schizophrenia. Multiple transcript variants encoding distinct isoforms have been identified for this gene.
Cellular Localization: Cytoplasm -
Molekulargewicht
- 39 kDa
-
Gen-ID
- 84062
-
UniProt
- Q96EV8
-
Pathways
- Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling
Target
-