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14-3-3 zeta Antikörper (Center)

Dieses Anti-14-3-3 zeta-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von 14-3-3 zeta in WB, IF, IHC (p) und ICC. Geeignet für Human und Maus.
Produktnummer ABIN2854923

Kurzübersicht für 14-3-3 zeta Antikörper (Center) (ABIN2854923)

Target

Alle 14-3-3 zeta (YWHAZ) Antikörper anzeigen
14-3-3 zeta (YWHAZ)

Reaktivität

  • 141
  • 78
  • 65
  • 11
  • 10
  • 8
  • 8
  • 8
  • 6
  • 5
  • 5
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
Human, Maus

Wirt

  • 126
  • 17
Kaninchen

Klonalität

  • 127
  • 16
Polyklonal

Konjugat

  • 84
  • 10
  • 7
  • 6
  • 5
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser 14-3-3 zeta Antikörper ist unkonjugiert

Applikation

  • 130
  • 67
  • 61
  • 32
  • 30
  • 21
  • 18
  • 16
  • 13
  • 13
  • 4
  • 3
  • 2
  • 1
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
  • Bindungsspezifität

    • 29
    • 17
    • 10
    • 9
    • 9
    • 8
    • 7
    • 7
    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Center

    Kreuzreaktivität

    Rhesusaffen, Rind (Kuh)

    Kreuzreaktivität (Details)

    Rhesus Monkey (100 %), Bovine (100 %)

    Produktmerkmale

    Rabbit Polyclonal antibody to 14-3-3 zeta (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide)
    14-3-3 zeta antibody

    Aufreinigung

    Purified by antigen-affinity chromatography.

    Immunogen

    Recombinant protein encompassing a sequence within the center region of human 14-3-3 zeta. The exact sequence is proprietary.

    Isotyp

    IgG
  • Applikationshinweise

    Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*

    Kommentare

    Positive Control: 293T , A431 , H1299 , HeLaS3 , HepG2 , Molt-4 , Raji , NIH-3T3

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    0.7 mg/mL

    Buffer

    0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

    Konservierungsmittel

    Thimerosal (Merthiolate)

    Vorsichtsmaßnahmen

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target

    14-3-3 zeta (YWHAZ)

    Andere Bezeichnung

    14-3-3 zeta

    Hintergrund

    This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99 % identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Several transcript variants that differ in the 5' UTR but that encode the same protein have been identified for this gene.

    Cellular Localization: Cytoplasm , Melanosome

    Molekulargewicht

    28 kDa

    Gen-ID

    7534

    Pathways

    Apoptose, Hormone Transport, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Synaptic Membrane, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location
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