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SYK Antikörper (Internal Region)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch SYK in WB, IF, IP, IHC (p) und ICC. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.
Produktnummer ABIN2854855

Kurzübersicht für SYK Antikörper (Internal Region) (ABIN2854855)

Target

Alle SYK Antikörper anzeigen
SYK (Spleen tyrosine Kinase (SYK))

Reaktivität

  • 174
  • 91
  • 56
  • 10
  • 5
  • 5
  • 4
  • 3
  • 3
  • 1
  • 1
Human, Maus, Ratte

Wirt

  • 159
  • 22
  • 3
Kaninchen

Klonalität

  • 160
  • 23
Polyklonal

Konjugat

  • 105
  • 10
  • 8
  • 6
  • 5
  • 5
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
Dieser SYK Antikörper ist unkonjugiert

Applikation

  • 139
  • 73
  • 48
  • 21
  • 21
  • 18
  • 14
  • 14
  • 12
  • 10
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
  • Bindungsspezifität

    • 34
    • 30
    • 19
    • 16
    • 11
    • 8
    • 8
    • 8
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region

    Kreuzreaktivität

    Rind (Kuh)

    Kreuzreaktivität (Details)

    Bovine (80 %)

    Produktmerkmale

    Rabbit Polyclonal antibody to SYK (spleen tyrosine kinase)
    SYK antibody [N2C2], Internal

    Aufreinigung

    Purified by antigen-affinity chromatography.

    Immunogen

    Recombinant protein encompassing a sequence within the center region of human SYK. The exact sequence is proprietary.

    Isotyp

    IgG
  • Applikationshinweise

    Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Immunoprecipitation 1:100-1:500* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Immunoprecipitation1:100-1:500* Western blot1:500-1:3000*

    Kommentare

    Positive Control: A431 , Raji , BMDM , mouse spleen

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    0.85 mg/mL

    Buffer

    1XPBS, 20 % Glycerol ( pH 7). 0.025 % ProClin 300 was added as a preservative.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target

    SYK (Spleen tyrosine Kinase (SYK))

    Andere Bezeichnung

    SYK

    Hintergrund

    This gene encodes a member of the family of non-receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

    Molekulargewicht

    72 kDa

    Gen-ID

    6850

    Pathways

    Fc-epsilon Rezeptor Signalübertragung, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Thromboxane A2 Receptor Signaling, BCR Signaling
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