FOXO3 Antikörper (C-Term)
Kurzübersicht für FOXO3 Antikörper (C-Term) (ABIN2854686)
Target
Alle FOXO3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Güteklasse
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Bindungsspezifität
- C-Term
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Kreuzreaktivität
- Human, Maus, Ratte, Eichhörnchen, Xenopus laevis
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Produktmerkmale
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Rabbit Polyclonal antibody to FOXO3A (forkhead box O3)
FOXO3A antibody [C3], C-term -
Aufreinigung
- Purified by antigen-affinity chromatography.
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Immunogen
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human FOXO3A. The exact sequence is proprietary.
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Isotyp
- IgG
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Applikationshinweise
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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Kommentare
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Positive Control: Mouse brain , C2C12
Validation: KO/KD, Orthogonal
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.56 mg/mL
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Buffer
- 1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- FOXO3 (Forkhead Box O3 (FOXO3))
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Andere Bezeichnung
- forkhead box O3
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Hintergrund
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This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia. Alternatively spliced transcript variants encoding the same protein have been observed.
Cellular Localization: Cytoplasm , cytosol , Nucleus -
Molekulargewicht
- 71 kDa
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Gen-ID
- 2309
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UniProt
- O43524
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Pathways
- Zellzyklus, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Carbohydrate Homeostasis
Target
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