LC3B Antikörper

Produktnummer ABIN2854667

Der Kaninchen Polyklonal Anti-LC3B-Antikörper wurde für WB und IHC (p) validiert. Er ist geeignet, LC3B in Proben von Ratte zu detektieren. Es sind 2+ Publikationen verfügbar.

Kurzübersicht für LC3B Antikörper (ABIN2854667)

Target: LC3B (MAP1LC3B) (Microtubule-Associated Protein 1 Light Chain 3 beta (MAP1LC3B))

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LC3B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-LC3B Antikörper

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Rabbit Polyclonal antibody to LC3B (microtubule-associated protein 1 light chain 3 beta)
LC3B antibody

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Full length rat LC3B Recombinant protein.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:10000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

virus infected Huh7 , PC-3 , mouse brain , rat brain extract , U87-MG , SK-N-SH , IMR32 , SK-N-AS

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Referenzen für anti-LC3B Antikörper (ABIN2854667)

Qi, Ren, Ba, Song, Zhang, Cao, Shi, Fu, Liu, Sun: "MSTN Attenuates Cardiac Hypertrophy through Inhibition of Excessive Cardiac Autophagy by Blocking AMPK /mTOR and miR-128/PPARγ/NF-κB." in: Molecular therapy. Nucleic acids, Vol. 19, pp. 507-522, (2020) (PubMed).

Wei, Chen, Chen, Lou, Lin, Hung, Hsiao, Yao, Shieh: "Autophagy promotes resistance to photodynamic therapy-induced apoptosis selectively in colorectal cancer stem-like cells." in: Autophagy, Vol. 10, Issue 7, pp. 1179-92, (2015) (PubMed).

Details zu LC3B

Target: LC3B (MAP1LC3B) (Microtubule-Associated Protein 1 Light Chain 3 beta (MAP1LC3B))

Andere Bezeichnung: microtubule-associated protein 1 light chain 3 beta

Hintergrund: May mediate MAPlA and MAPlB microtubule binding activity during development of the nervous system [RGD]

Cellular Localization: Cytoplasm , Endomembrane system, Lipid-anchor , Cytoplasmic vesicle , autophagosome membrane, Lipid-anchor

Molekulargewicht: 16 kDa

Gen-ID: 64862

UniProt: Q62625

Pathways: Autophagie