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desert Hedgehog Antikörper (Center)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch desert Hedgehog in WB. Er zeigt eine Reaktivität gegenüber Human.
Produktnummer ABIN2854606

Kurzübersicht für desert Hedgehog Antikörper (Center) (ABIN2854606)

Target

Alle desert Hedgehog (DHH) Antikörper anzeigen
desert Hedgehog (DHH) (Desert Hedgehog (DHH))

Reaktivität

  • 40
  • 15
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 43
  • 4
  • 2
  • 2
Kaninchen

Klonalität

  • 47
  • 4
Polyklonal

Konjugat

  • 31
  • 7
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser desert Hedgehog Antikörper ist unkonjugiert

Applikation

  • 39
  • 17
  • 15
  • 8
  • 5
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)
  • Bindungsspezifität

    • 7
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Center

    Kreuzreaktivität

    Maus, Ratte (Rattus)

    Kreuzreaktivität (Details)

    Mouse (98 %), Rat (98 %)

    Produktmerkmale

    Rabbit polyclonal antibody to Dhh (desert hedgehog homolog (Drosophila))
    Dhh antibody [N3C3]

    Aufreinigung

    Purified by antigen-affinity chromatography.

    Immunogen

    Recombinant protein encompassing a sequence within the center region of human Dhh. The exact sequence is proprietary.

    Isotyp

    IgG
  • Applikationshinweise

    Suggested dilution Reference Western blot 1:5000-1:20000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:5000-1:20000*

    Kommentare

    Positive Control: 293T , A431 , Jurkat , Raji

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    0.95 mg/mL

    Buffer

    0.1M Tris, 0.1M Glycine, 20 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

    Konservierungsmittel

    Thimerosal (Merthiolate)

    Vorsichtsmaßnahmen

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target

    desert Hedgehog (DHH) (Desert Hedgehog (DHH))

    Andere Bezeichnung

    Dhh

    Substanzklasse

    Species

    Hintergrund

    This gene encodes a member of the Hedgehog family. The hedgehog gene family encodes signaling molecules that play an important role in regulating morphogenesis. This protein is predicted to be made as a precursor that is autocatalytically cleaved, the N-terminal portion is soluble and contains the signalling activity while the C-terminal portion is involved in precursor processing. More importantly, the C-terminal product covalently attaches a cholesterol moiety to the N-terminal product, restricting the N-terminal product to the cell surface and preventing it from freely diffusing throughout the organism. Defects in this protein have been associated with partial gonadal dysgenesis (PGD) accompanied by minifascicular polyneuropathy. This protein may be involved in both male gonadal differentiation and perineurial development.

    Cellular Localization: Desert hedgehog protein N-product: Cell membrane, Lipid-anchor, Extracellular side , Desert hedgehog protein C-product: Secreted , extracellular space , Desert hedgehog protein N-product: Cell membrane , Desert hedgehog protein C-product: Secreted , extra

    Molekulargewicht

    44 kDa

    Gen-ID

    50846

    Pathways

    Hedgehog Signalweg
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