CD3D Antikörper (Center)
Kurzübersicht für CD3D Antikörper (Center) (ABIN2854530)
Target
Alle CD3D Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- Center
-
Produktmerkmale
-
Rabbit Polyclonal antibody to CD3 delta (CD3d molecule, delta (CD3-TCR complex))
CD3 delta antibody -
Aufreinigung
- Purified by antigen-affinity chromatography.
-
Immunogen
- Recombinant protein encompassing a sequence within the center region of human CD3 delta. The exact sequence is proprietary.
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
- Suggested dilution Reference Western blot 1:5000-1:20000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:5000-1:20000*
-
Kommentare
-
Positive Control: Jurkat membrane
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- 1 mg/mL
-
Buffer
- 1XPBS, 20 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
-
Konservierungsmittel
- Thimerosal (Merthiolate)
-
Vorsichtsmaßnahmen
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
-
-
- CD3D (CD3d Molecule, delta (CD3-TCR Complex) (CD3D))
-
Andere Bezeichnung
- CD3 delta
-
Hintergrund
-
The protein encoded by this gene is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. The encoded membrane protein represents the delta subunit of the CD3 complex, and along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in this gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK). Two transcript variants encoding different isoforms have been found for this gene. Other variants may also exist, but the full-length natures of their transcripts has yet to be defined.
Cellular Localization: Membrane -
Molekulargewicht
- 19 kDa
-
Gen-ID
- 915
-
Pathways
- T-Zell Rezeptor Signalweg, CXCR4-mediated Signaling Events
Target
-