GCS1 Antikörper
Kurzübersicht für GCS1 Antikörper (ABIN2854529)
Target
Alle GCS1 (MOGS) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Kreuzreaktivität
- Human
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Produktmerkmale
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Rabbit polyclonal antibody to Glucosidase I (mannosyl-oligosaccharide glucosidase )
Glucosidase I antibody [N1N3] -
Aufreinigung
- Purified by antigen-affinity chromatography.
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Immunogen
- Recombinant protein encompassing a sequence within the center region of human Glucosidase I. The exact sequence is proprietary.
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Isotyp
- IgG
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Applikationshinweise
- WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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Kommentare
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Positive Control: H1299
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
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Konservierungsmittel
- Thimerosal (Merthiolate)
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Vorsichtsmaßnahmen
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- GCS1 (MOGS) (Mannosyl-Oligosaccharide Glucosidase (MOGS))
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Andere Bezeichnung
- mannosyl-oligosaccharide glucosidase
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Hintergrund
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This gene encodes the first enzyme in the N-linked oligosaccharide processing pathway. The enzyme cleaves the distal alpha-1,2-linked glucose residue from the Glc(3)-Man(9)-GlcNAc(2) oligosaccharide precursor. This protein is located in the lumen of the endoplasmic reticulum. Defects in this gene are a cause of type IIb congenital disorder of glycosylation (CDGIIb). Two transcript variants encoding different isoforms have been found for this gene.
Cellular Localization: Endoplasmic reticulum membrane, Single-pass type II membrane protein -
Molekulargewicht
- 92 kDa
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Gen-ID
- 7841
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UniProt
- Q13724
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Pathways
- SARS-CoV-2 Protein Interaktom
Target
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