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CHRNA3 Antikörper (Center)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch CHRNA3 in WB, ICC und IF. Er zeigt eine Reaktivität gegenüber Human.
Produktnummer ABIN2854522

Kurzübersicht für CHRNA3 Antikörper (Center) (ABIN2854522)

Target

Alle CHRNA3 Antikörper anzeigen
CHRNA3 (Cholinergic Receptor, Nicotinic, alpha 3 (Neuronal) (CHRNA3))

Reaktivität

  • 57
  • 20
  • 20
  • 7
  • 6
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
Human

Wirt

  • 55
  • 3
Kaninchen

Klonalität

  • 55
  • 3
Polyklonal

Konjugat

  • 30
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser CHRNA3 Antikörper ist unkonjugiert

Applikation

  • 48
  • 19
  • 18
  • 13
  • 13
  • 7
  • 5
  • 5
  • 4
  • 3
  • 1
  • 1
Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)
  • Bindungsspezifität

    • 15
    • 8
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Center

    Kreuzreaktivität

    Maus, Huhn, Ratte (Rattus), Rind (Kuh)

    Kreuzreaktivität (Details)

    Mouse (94 %), Chicken (87 %), Rat (94 %), Bovine (96 %)

    Produktmerkmale

    Rabbit Polyclonal antibody to AChR alpha 3
    AChR alpha 3 antibody

    Aufreinigung

    Purified by antigen-affinity chromatography.

    Immunogen

    Recombinant protein encompassing a sequence within the center region of human Nicotinic Acetylcholine Receptor alpha 3. The exact sequence is proprietary.

    Isotyp

    IgG
  • Applikationshinweise

    Suggested dilution Reference ICC/IF 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* Western blot1:500-1:3000*

    Kommentare

    Positive Control: Molt-4

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 mg/mL

    Buffer

    0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

    Konservierungsmittel

    Thimerosal (Merthiolate)

    Vorsichtsmaßnahmen

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target

    CHRNA3 (Cholinergic Receptor, Nicotinic, alpha 3 (Neuronal) (CHRNA3))

    Andere Bezeichnung

    AChR alpha 3

    Hintergrund

    This locus encodes a member of the nicotinic acetylcholine receptor family of proteins. Members of this family of proteins form pentameric complexes comprised of both alpha and beta subunits. This locus encodes an alpha-type subunit, as it contains characteristic adjacent cysteine residues. The encoded protein is a ligand-gated ion channel that likely plays a role in neurotransmission. Polymorphisms in this gene have been associated with an increased risk of smoking initiation and an increased susceptibility to lung cancer. Alternatively spliced transcript variants have been described.

    Cellular Localization: Cell junction , synapse , postsynaptic cell membrane , Cell membrane

    Molekulargewicht

    57 kDa

    Gen-ID

    1136

    Pathways

    Synaptic Membrane
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