CHRNA3 Antikörper (AA 32-240)

Produktnummer ABIN5611357

Produktdetails anti-CHRNA3 Antikörper

Target: CHRNA3 (Cholinergic Receptor, Nicotinic, alpha 3 (Neuronal) (CHRNA3))

Bindungsspezifität: AA 32-240

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CHRNA3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS), Neutralization (Neut)

Aufreinigung: purified

Immunogen: Purified recombinant fragment of human CHRNA3 (AA: 32-240) expressed in E. coli.

Klon: 6D3A10

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400, IHC: N/A

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: 4°C, -20°C for long term storage

Referenzen für anti-CHRNA3 Antikörper (ABIN5611357)

Kulbatskii, Shenkarev, Bychkov, Loktyushov, Shulepko, Koshelev, Povarov, Popov, Peigneur, Chugunov, Kozlov, Sharonova, Efremov, Skrebitsky, Tytgat, Kirpichnikov, Lyukmanova: "Human Three-Finger Protein Lypd6 Is a Negative Modulator of the Cholinergic System in the Brain." in: Frontiers in cell and developmental biology, Vol. 9, pp. 662227, (2021) (PubMed).

Details zu CHRNA3

Target: CHRNA3 (Cholinergic Receptor, Nicotinic, alpha 3 (Neuronal) (CHRNA3))

Andere Bezeichnung: CHRNA3 (CHRNA3 Produkte)

Synonyme: LNCR2 antikoerper, NACHRA3 antikoerper, PAOD2 antikoerper, (a)3 antikoerper, A730007P14Rik antikoerper, Acra-3 antikoerper, Acra3 antikoerper, cholinergic receptor nicotinic alpha 3 subunit antikoerper, cholinergic receptor, nicotinic, alpha polypeptide 3 antikoerper, CHRNA3 antikoerper, Chrna3 antikoerper

Hintergrund:

Description: This locus encodes a member of the nicotinic acetylcholine receptor family of proteins. Members of this family of proteins form pentameric complexes comprised of both alpha and beta subunits. This locus encodes an alpha-type subunit, as it contains characteristic adjacent cysteine residues. The encoded protein is a ligand-gated ion channel that likely plays a role in neurotransmission. Polymorphisms in this gene have been associated with an increased risk of smoking initiation and an increased susceptibility to lung cancer. Alternatively spliced transcript variants have been described.

Aliases: LNCR2, PAOD2, NACHRA3

Molekulargewicht: 57.5 kDa

Gen-ID: 1136

HGNC: 1136

Pathways: Synaptic Membrane