ATF6 Antikörper (C-Term)

Produktnummer ABIN2854487

Der Kaninchen Polyklonal Anti-ATF6-Antikörper wurde für WB validiert. Er ist geeignet, ATF6 in Proben von Human zu detektieren. Es ist 1 Publikation verfügbar.

Kurzübersicht für ATF6 Antikörper (C-Term) (ABIN2854487)

Target: ATF6 (Activating Transcription Factor 6 (ATF6))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ATF6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Güteklasse: KO Validated

Produktdetails anti-ATF6 Antikörper

Bindungsspezifität: C-Term

Spezifität: This antibody was raised against the C-terminus of human ATF6 alpha, meaning it can only detect the uncleaved form.,Knockdown/Knockout validation was supported by references (PMID:29535165)

Kreuzreaktivität: Human, Maus

Produktmerkmale: Rabbit polyclonal antibody to ATF6 (activating transcription factor 6)
ATF6 antibody [C3], C-term

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human ATF6. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

Validatio: KO/KD, Orthogonal

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Referenzen für anti-ATF6 Antikörper (ABIN2854487)

Wang, Lai, Yang, Lin, Chen, Tsai: "Counteracting Cisplatin-Induced Testicular Damages by Natural Polyphenol Constituent Honokiol." in: Antioxidants (Basel, Switzerland), Vol. 9, Issue 8, (2020) (PubMed).

Details zu ATF6

Target: ATF6 (Activating Transcription Factor 6 (ATF6))

Andere Bezeichnung: activating transcription factor 6

Hintergrund: ATF6 is an endoplasmic reticulum (ER) stress-regulated transmembrane transcription factor that activates the transcription of ER molecules.[supplied by OMIM]

Cellular Localization: Endoplasmic reticulum membrane , Processed cyclic AMP-dependent transcription factor ATF-6 alpha: Nucleus

Molekulargewicht: 75 kDa

Gen-ID: 22926

UniProt: P18850

Pathways: ER-Nucleus Signaling, Unfolded Protein Response