PTK7 Antikörper (C-Term)

Produktnummer ABIN2854472

Der Kaninchen Polyklonal Anti-PTK7-Antikörper wurde für FACS validiert. Er ist geeignet, PTK7 in Proben von Human zu detektieren. Es ist 1 Publikation verfügbar.

Kurzübersicht für PTK7 Antikörper (C-Term) (ABIN2854472)

Target: PTK7 (PTK7 Protein tyrosine Kinase 7 (PTK7))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PTK7 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Produktdetails anti-PTK7 Antikörper

Bindungsspezifität: C-Term

Kreuzreaktivität: Human

Produktmerkmale: Rabbit polyclonal antibody to CCK4 (CCK4 protein tyrosine kinase 7)
CCK4 antibody [C1C3]

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human CCK4. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.36 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Referenzen für anti-PTK7 Antikörper (ABIN2854472)

Chen, Khatri, Mazur, Polin, Zheng, Vaka, Hoang, Shrager, Xu, Vicent, Butte, Sweet-Cordero: "A meta-analysis of lung cancer gene expression identifies PTK7 as a survival gene in lung adenocarcinoma." in: Cancer research, Vol. 74, Issue 10, pp. 2892-902, (2014) (PubMed).

Details zu PTK7

Target: PTK7 (PTK7 Protein tyrosine Kinase 7 (PTK7))

Andere Bezeichnung: protein tyrosine kinase 7 (inactive)

Hintergrund: Receptor protein tyrosine kinases transduce extracellular signals across the cell membrane. A subgroup of these kinases lack detectable catalytic tyrosine kinase activity but retain roles in signal transduction. The protein encoded by this gene is a member of this subgroup of tyrosine kinases and may function as a cell adhesion molecule. This gene is thought to be expressed in colon carcinomas but not in normal colon, and therefore may be a marker for or may be involved in tumor progression. Four transcript variants encoding four different isoforms have been found for this gene.

Cellular Localization: Membrane, Single-pass type I membrane protein

Molekulargewicht: 118 kDa

Gen-ID: 5754

UniProt: Q13308

Pathways: RTK Signalweg, Tube Formation