GSTM5 Antikörper

Produktnummer ABIN2854454

Der Kaninchen Polyklonal Anti-GSTM5-Antikörper wurde für WB validiert. Er ist geeignet, GSTM5 in Proben von Human zu detektieren.

Kurzübersicht für GSTM5 Antikörper (ABIN2854454)

Target: GSTM5 (Glutathione S-Transferase mu 5 (GSTM5))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GSTM5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-GSTM5 Antikörper

Kreuzreaktivität: Maus

Produktmerkmale: Rabbit Polyclonal antibody to GSTM5 (glutathione S-transferase mu 5)
GSTM5 antibody

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human GSTM5. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: Mouse brain

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu GSTM5

Target: GSTM5 (Glutathione S-Transferase mu 5 (GSTM5))

Andere Bezeichnung: glutathione S-transferase mu 5

Hintergrund: Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Diversification of these genes has occurred in regions encoding substrate-binding domains, as well as in tissue expression patterns, to accommodate an increasing number of foreign compounds.

Cellular Localization: Cytoplasm

Molekulargewicht: 26 kDa

Gen-ID: 2949

UniProt: P46439