GSTM5 Antikörper (N-Term)

Produktnummer ABIN952643

Der Kaninchen Polyklonal anti-GSTM5 Antikörper wird verwendet zum Nachweis von GSTM5 in Proben von Human. Er wurde validiert für WB, FACS, IHC (p) und EIA.

Kurzübersicht für GSTM5 Antikörper (N-Term) (ABIN952643)

Target: GSTM5 (Glutathione S-Transferase mu 5 (GSTM5))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GSTM5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-GSTM5 Antikörper

Bindungsspezifität: AA 21-51, N-Term

Spezifität: This antibody recognizes Human GSTM5 (N-term).

Aufreinigung: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 21-51 amino acids from the N-terminal region of Human GSTM5

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu GSTM5

Target: GSTM5 (Glutathione S-Transferase mu 5 (GSTM5))

Andere Bezeichnung: GSTM5

Hintergrund: Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Diversification of these genes has occurred in regions encoding substrate-binding domains, as well as in tissue expression patterns, to accommodate an increasing number of foreign compounds.Synonyms: GST class-mu 5, GSTM5-5, Glutathione S-transferase Mu 5

Molekulargewicht: 25675 Da

Gen-ID: 2949

NCBI Accession: NP_000842