ECEL1 Antikörper

Produktnummer ABIN2854447

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch ECEL1 in WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für ECEL1 Antikörper (ABIN2854447)

Target: ECEL1 (Endothelin Converting Enzyme-Like 1 (ECEL1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ECEL1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ECEL1 Antikörper

Kreuzreaktivität: Human

Produktmerkmale: Rabbit polyclonal antibody to ECEL1 (endothelin converting enzyme-like 1)
ECEL1 antibody [N3C2], Internal

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human ECEL1. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: ECEL1 transfected 293T

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.4 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu ECEL1

Target: ECEL1 (Endothelin Converting Enzyme-Like 1 (ECEL1))

Andere Bezeichnung: endothelin converting enzyme like 1

Hintergrund: This gene encodes a member of the M13 family of endopeptidases. In general, M13 family members are zinc-containing type II integral-membrane proteins that are important regulators of neuropeptide and peptide hormone activity. This gene is expressed specifically in the central nervous system and its protein localizes predominately to the endoplasmic reticulum or, in trace amounts, to the cell surface. Disruption of this gene in mouse embryonic stem cells results in neonatal lethality due to respiratory failure shortly after birth. Based on the specific expression of this gene and the phenotype of the gene deficiency in mouse embryos, it is suggested that this protein plays a critical role in neural regulation of the respiratory system. This gene has multiple pseudogenes.

Cellular Localization: Membrane

Molekulargewicht: 88 kDa

Gen-ID: 9427

UniProt: O95672