nectin-3 Antikörper (Center)
Kurzübersicht für nectin-3 Antikörper (Center) (ABIN2854443)
Target
Alle nectin-3 (NECTIN3) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- Center
-
Kreuzreaktivität
- Maus, Ratte (Rattus)
-
Kreuzreaktivität (Details)
- Mouse (94 %), Rat (94 %)
-
Produktmerkmale
-
Rabbit polyclonal antibody to Nectin 3 (poliovirus receptor-related 3)
Nectin 3 antibody -
Aufreinigung
- Purified by antigen-affinity chromatography.
-
Immunogen
- Recombinant protein encompassing a sequence within the center region of human Nectin 3. The exact sequence is proprietary.
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
- Suggested dilution Reference Western blot 1:1000-1:10000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:1000-1:10000*
-
Kommentare
-
Positive Control: K562 , THP-1
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- 1 mg/mL
-
Buffer
- 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
-
Konservierungsmittel
- Thimerosal (Merthiolate)
-
Vorsichtsmaßnahmen
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
-
-
- nectin-3 (NECTIN3) (Nectin cell adhesion molecule 3 (NECTIN3))
-
Andere Bezeichnung
- Nectin 3
-
Hintergrund
-
Nectins (e.g., PVRL1, MIM 600644) are immunoglobulin-like adhesion molecules that interact with afadin (AF6, MIM 159559). Afadin is an actin filament-binding protein that connects nectins to the actin cytoskeleton. The nectin-afadin system organizes adherens junctions cooperatively with the cadherin (see MIM 192090)-catenin (see MIM 116805) system in epithelial cells.[supplied by OMIM]
Cellular Localization: Cell membrane, Single-pass membrane protein -
Molekulargewicht
- 61 kDa
-
Gen-ID
- 25945
-
Pathways
- Cell-Cell Junction Organization
Target
-