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Chitotriosidase 1 Antikörper

This anti-Chitotriosidase 1 antibody (ABIN2854344) is a Rabbit Polyclonal antibody detecting Chitotriosidase 1 in WB. Suitable for Human.
Produktnummer ABIN2854344

Kurzübersicht für Chitotriosidase 1 Antikörper (ABIN2854344)

Target

Alle Chitotriosidase 1 (CHIT1) Antikörper anzeigen
Chitotriosidase 1 (CHIT1) (Chitotriosidase (CHIT1))

Reaktivität

  • 36
  • 9
  • 3
Human

Wirt

  • 31
  • 11
  • 1
Kaninchen

Klonalität

  • 34
  • 9
Polyklonal

Konjugat

  • 31
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Chitotriosidase 1 Antikörper ist unkonjugiert

Applikation

  • 29
  • 18
  • 14
  • 11
  • 10
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB)
  • Kreuzreaktivität

    Human

    Produktmerkmale

    Rabbit polyclonal antibody to Chitotriosidase (chitinase 1 (chitotriosidase))
    Chitotriosidase antibody [N3C3]

    Aufreinigung

    Purified by antigen-affinity chromatography.

    Immunogen

    Recombinant protein encompassing a sequence within the center region of human CHIT1. The exact sequence is proprietary.

    Isotyp

    IgG
  • Applikationshinweise

    WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    Kommentare

    Positive Control: HeLa

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 mg/mL

    Buffer

    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

    Konservierungsmittel

    Thimerosal (Merthiolate)

    Vorsichtsmaßnahmen

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target

    Chitotriosidase 1 (CHIT1) (Chitotriosidase (CHIT1))

    Andere Bezeichnung

    chitinase 1

    Hintergrund

    Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens.

    Cellular Localization: Secreted , Lysosome

    Molekulargewicht

    52 kDa

    Gen-ID

    1118

    UniProt

    Q13231
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