Tec Protein Tyrosine Kinase (TEC) (Middle Region) Antikörper

Produktnummer ABIN2853628

Der Kaninchen Polyklonal anti-Tec Protein Tyrosine Kinase Antikörper wird verwendet zum Nachweis von Tec Protein Tyrosine Kinase in Proben von Human und Maus. Er wurde validiert für WB, IHC (p) und EIA.

Kurzübersicht für Tec Protein Tyrosine Kinase (TEC) (Middle Region) Antikörper (ABIN2853628)

Target: Tec Protein Tyrosine Kinase (TEC)

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails

Bindungsspezifität: Middle Region

Spezifität: This antibody reacts to TEC.

Aufreinigung: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the center region of human TEC.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Antigendetails

Target: Tec Protein Tyrosine Kinase (TEC)

Andere Bezeichnung: TEC

Hintergrund: TEC belongs to the TEC subfamily of non-receptor protein-tyrosine kinases containing a pleckstrin homology domain. TEC family kinases are involved in the intracellular signaling mechanisms of cytokine receptors, lymphocyte surface antigens, heterotrimeric G-protein coupled receptors, and integrin molecules. They are also key players in the regulation of the immune functions. TEC kinase is an integral component of T cell signaling and has a distinct role in T cell activation. TEC may be associated with myelodysplastic syndrome.Synonyms: PSCTK4, Tyrosine-protein kinase Tec

Gen-ID: 7006, 5874

UniProt: P42680

Pathways: Fc-epsilon Rezeptor Signalübertragung