NLRP2 Antikörper
Kurzübersicht für NLRP2 Antikörper (ABIN363311)
Target
Alle NLRP2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Spezifität
- Reacts with NBS1 from human, mouse, hamster and primate
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Aufreinigung
- Antiserum
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Immunogen
- Partial length human NBS1 protein [Swiss-Prot# O60934].
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Applikationshinweise
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Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
- ICC : 1/50 to 1/200 - IF : 1/200 - IP : 3 μL - WB : 1/1000 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- , Sodium azide 0.02 %
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C/-80 °C
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Informationen zur Lagerung
- Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.
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- NLRP2 (NLR Family, Pyrin Domain Containing 2 (NLRP2))
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Andere Bezeichnung
- Nijmegen Breakage Syndrome 1 (NBS1)
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Hintergrund
- The p95 gene (identical to NBS1 and nibrin) is a member of the hMre11/hRad50 double-strand break complex.This protein complex has been implicated in Nijmegen breakage syndrome, an autosomal recessive disorder marked by increased cancer incidence, cell cycle checkpoint deficits, and ionizing radiation sensitivity, thus revealing a direct molecular link between double-strand break repair and cell cycle checkpoint functions.
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Pathways
- Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Inflammasome
Target
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