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ALDH2 Antikörper

Der Kaninchen Polyklonal Anti-ALDH2-Antikörper wurde für WB, FACS und IHC (p) validiert. Er ist geeignet, ALDH2 in Proben von Human zu detektieren. Es sind 3+ Publikationen verfügbar.
Produktnummer ABIN1881053

Kurzübersicht für ALDH2 Antikörper (ABIN1881053)

Target

Alle ALDH2 Antikörper anzeigen
ALDH2 (Aldehyde Dehydrogenase 2 Family (Mitochondrial) (ALDH2))

Reaktivität

  • 78
  • 25
  • 24
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 61
  • 18
  • 2
Kaninchen

Klonalität

  • 57
  • 24
Polyklonal

Konjugat

  • 48
  • 9
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
Dieser ALDH2 Antikörper ist unkonjugiert

Applikation

  • 67
  • 40
  • 34
  • 19
  • 16
  • 12
  • 11
  • 11
  • 3
  • 2
Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon

RB23145
  • Aufreinigung

    This antibody is purified through a protein A column, followed by peptide affinity purification. Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

    Immunogen

    This ALDH2 antibody is generated from rabbits immunized with human ALDH2 recombinant protein.
  • Applikationshinweise

    WB: 1:1000,IHC (p): 1:50-100,FACS: 1:10-50

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    0.33 mg/mL

    Buffer

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
  • Guo, Wang, Liu, Chen, Qi, Guo: "Genetic polymorphisms in cytochrome P4502E1, alcohol and aldehyde dehydrogenases and the risk of esophageal squamous cell carcinoma in Gansu Chinese males." in: World journal of gastroenterology : WJG, Vol. 14, Issue 9, pp. 1444-9, (2008) (PubMed).

    Chen, Smith, Harbord, Lewis: "Alcohol intake and blood pressure: a systematic review implementing a Mendelian randomization approach." in: PLoS medicine, Vol. 5, Issue 3, pp. e52, (2008) (PubMed).

    Teeguarden, Bogdanffy, Covington, Tan, Jarabek: "A PBPK model for evaluating the impact of aldehyde dehydrogenase polymorphisms on comparative rat and human nasal tissue acetaldehyde dosimetry." in: Inhalation toxicology, Vol. 20, Issue 4, pp. 375-90, (2008) (PubMed).

  • Target

    ALDH2 (Aldehyde Dehydrogenase 2 Family (Mitochondrial) (ALDH2))

    Andere Bezeichnung

    ALDH2

    Hintergrund

    ALDH2 belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of this enzyme, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of Asians have only the cytosolic isozyme, missing the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Asians than among Caucasians could be related to the absence of the mitochondrial isozyme.

    Synonyms: ALDH2, ALDM, Aldehyde dehydrogenase, mitochondrial, ALDH class 2, ALDH-E2, ALDHI

    NCBI Accession

    NP_000681, NP_001191818

    UniProt

    P05091
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