CD24 Antikörper (N-Term)

Produktnummer ABIN652728

Dieses Anti-CD24-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von CD24 in FACS, WB und IHC (p). Geeignet für Human.

Kurzübersicht für CD24 Antikörper (N-Term) (ABIN652728)

Target: CD24 (CD24 Molecule (CD24))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD24 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RB23639

Produktdetails anti-CD24 Antikörper

Bindungsspezifität: AA 1-30, N-Term

Homologie: Mouse (Murine)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CD24 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 AA from the N-terminal region of human CD24.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Suggested dilutions:
WB = 1:1000, IHC (p) = 1:50-100, FACS = 1:10-50
Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handhabung: Avoid freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots.

Haltbarkeit: 6 months

Details zu CD24

Target: CD24 (CD24 Molecule (CD24))

Andere Bezeichnung: CD24

Hintergrund: Function:
Modulates B-cell activation responses. Signaling could be triggered by the binding of a lectin-like ligand to the CD24 carbohydrates, and transduced by the release of second messengers derived from the GPI-anchor. Promotes AG-dependent proliferation of B-cells, and prevents their terminal differentiation into antibody-forming cells.

Cellular Location:
Cell membrane, Lipid-anchor, GPI-anchor.

Tissue Location:
B-cells. Expressed in a number of B-cell lines including P32/ISH and Namalwa. Expressed in erythroleukemia cell and small cell lung carcinoma cell lines. Also expressed on the surface of T-cells

Synonyms: CD_antigen=CD24, Flags: Precursor, Small cell lung carcinoma cluster 4 antigen, Signal transducer CD24, CD24, CD24A

Molekulargewicht: 8097 Da

Gen-ID: 100133941

NCBI Accession: NP_037362

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation