HS1BP3 Antikörper (AA 51-130) (AbBy Fluor® 594)

Produktnummer ABIN2814514

Der Kaninchen Polyklonal Anti-HS1BP3-Antikörper wurde für IF (cc) und IF (p) validiert. Er ist geeignet, HS1BP3 in Proben von Human zu detektieren.

Kurzübersicht für HS1BP3 Antikörper (AA 51-130) (AbBy Fluor® 594) (ABIN2814514)

Target: HS1BP3 (HCLS1 Binding Protein 3 (HS1BP3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HS1BP3 Antikörper ist konjugiert mit AbBy Fluor® 594

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-HS1BP3 Antikörper (AbBy Fluor® 594)

Bindungsspezifität: AA 51-130

Kreuzreaktivität: Human

Homologie: Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human HS1BP3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu HS1BP3

Target: HS1BP3 (HCLS1 Binding Protein 3 (HS1BP3))

Andere Bezeichnung: HS1BP3

Hintergrund:

Synonyms: ETM2, FLJ14249, H1BP3_HUMAN, HCLS1 binding protein 3, HCLS1-binding protein 3, HS1 binding protein 3, HS1 BP3, HS1-BP3, HS1-binding protein 3, Hs1bp3, HSP1BP-3.

Background: HS1BP3 is a 392 amino acid protein that contains one PX (phox homology) domain, a leucine zipper, immunoreceptor tyrosine-based inhibitory motif-like motifs and multiple proline-rich regions. Expressed primarily in brain, HS1BP3 is encoded by a gene mapping to human chromosome 2p24.1. The gene encoding HS1BP3 is frequently mutated in familial essential tremor, a disorder characterized by kinetic tremor the the hands, voice or head, though there is no correlation to Parkinson disease. HS1BP3 interacts with HAX-1?s SH3 domain, and may also play a role in the regulation of catecholamine and serotonin metabolism. Acting as a regulator of IL-2 signaling, HS1BP3 is likely involved in lymphocyte activation.