HDAC4 Antikörper (pSer246) (AbBy Fluor® 594)

Produktnummer ABIN2814205

Der Kaninchen Polyklonal Anti-HDAC4-Antikörper wurde für IF (p) validiert. Er ist geeignet, HDAC4 in Proben von Human zu detektieren.

Kurzübersicht für HDAC4 Antikörper (pSer246) (AbBy Fluor® 594) (ABIN2814205)

Target: HDAC4 (Histone Deacetylase 4 (HDAC4))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HDAC4 Antikörper ist konjugiert mit AbBy Fluor® 594

Applikation: Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-HDAC4 Antikörper (AbBy Fluor® 594)

Bindungsspezifität: pSer246

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human HDAC4 around the phosphorylation site of Ser246

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P)(1:50-200)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at 4°C

Haltbarkeit: 12 months

Details zu HDAC4

Target: HDAC4 (Histone Deacetylase 4 (HDAC4))

Andere Bezeichnung: HDAC4

Hintergrund:

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3. [provided by RefSeq, Jul 2008].

Subcellular location: Secreted

Synonyms: HDAC4Ser246, HDAC4S246, p-HDAC4Ser246, p-HDAC4S246, HD 4, HD4, HDAC 4, HDAC A, HDACA, Histone Deacetylase 4, Histone Deacetylase A, KIAA0288, EC 3.5.1.98, HA6116, HDA4_CAEEL, Histone deacetylase 4, CeHDA-7, Histone deacetylase 7.

Gen-ID: 9759

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process