Dysferlin Antikörper (AA 1901-2119) (AbBy Fluor® 594)

Produktnummer ABIN2812578

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Dysferlin in FACS. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Dysferlin Antikörper (AA 1901-2119) (AbBy Fluor® 594) (ABIN2812578)

Target: Dysferlin (DYSF)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Dysferlin Antikörper ist konjugiert mit AbBy Fluor® 594

Applikation: Flow Cytometry (FACS)

Produktdetails anti-Dysferlin Antikörper (AbBy Fluor® 594)

Bindungsspezifität: AA 1901-2119

Kreuzreaktivität: Human

Homologie: Mouse,Rat,Dog,Cow,Pig,Horse,Rabbit,Guinea Pig

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DYSF

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: FCM 1:20-100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu Dysferlin

Target: Dysferlin (DYSF)

Andere Bezeichnung: Dysferlin

Hintergrund:

Synonyms: DMAT, DYSF, Dysferlin Dystrophy associated fer 1 like protein Fer 1 like protein 1, Dysferlin limb girdle muscular dystrophy 2B autosomal recessive, Dysferlin limb girdle muscular dystrophy 2B, Dystrophy associated fer 1 like 1, Dystrophy associated fer 1 like protein, Dystrophy associated fer1 like 1, Dystrophy associated fer1 like protein, Fer 1 like protein 1, Fer1 like protein 1, FER1L1, FLJ00175, FLJ90168, LGMD 2B, LGMD2B, Limb girdle muscular dystrophy 2B autosomal recessive , Limb girdle muscular dystrophy 2B, Miyoshi myopathy, MM, DYSF_HUMAN.

Background: The protein encoded by this gene belongs to the ferlin family and is a skeletal muscle protein found associated with the sarcolemma. It is involved in muscle contraction and contains C2 domains that play a role in calcium-mediated membrane fusion events, suggesting that it may be involved in membrane regeneration and repair. In addition, the protein encoded by this gene binds caveolin-3, a skeletal muscle membrane protein which is important in the formation of caveolae. Specific mutations in this gene have been shown to cause autosomal recessive limb girdle muscular dystrophy type 2B (LGMD2B) as well as Miyoshi myopathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2008].

Gen-ID: 8291

UniProt: O75923