DUSP7 Antikörper (AA 321-419) (AbBy Fluor® 594)
Kurzübersicht für DUSP7 Antikörper (AA 321-419) (AbBy Fluor® 594) (ABIN2812556)
Target
Alle DUSP7 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- AA 321-419
-
Kreuzreaktivität
- Human
-
Homologie
- Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit
-
Aufreinigung
- Purified by Protein A.
-
Immunogen
- KLH conjugated synthetic peptide derived from human DUSP7
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
-
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- 1 μg/μL
-
Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
-
Konservierungsmittel
- ProClin
-
Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
-
Haltbarkeit
- 12 months
-
-
- DUSP7 (Dual Specificity Phosphatase 7 (DUSP7))
-
Andere Bezeichnung
- DUSP7
-
Hintergrund
-
Synonyms: Dual specicity phosphatase 7, Dual specicity protein phosphatase 7, Dual specicity protein phosphatase PYST2, DUS7_HUMAN, Dusp7, Jnk Stimulatory Phosphatase 1, JSP1, MKPX, PYST2.
Background: Dual-specificity phosphatases (DUSPs) constitute a large heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine/threonine residues. DUSP7 belongs to a class of DUSPs, designated MKPs, that dephosphorylate MAPK (mitogen-activated protein kinase) proteins ERK (see MIM 601795), JNK (see MIM 601158), and p38 (see MIM 600289) with specificity distinct from that of individual MKP proteins. MKPs contain a highly conserved C-terminal catalytic domain and an N-terminal Cdc25 (see MIM 116947)-like (CH2) domain. MAPK activation cascades mediate various physiologic processes, including cellular proliferation, apoptosis, differentiation, and stress responses
-
Gen-ID
- 1849
-
Pathways
- Neurotrophin Signalübertragung, Activation of Innate immune Response, Toll-Like Receptors Cascades
Target
-