Serotonin Receptor 1E Antikörper (AA 1-120) (AbBy Fluor® 594)

Produktnummer ABIN2809301

Dieses Anti-Serotonin Receptor 1E-Antikörper ist ein Rabbit Polyclonal-Antikörper zur Detektion von Serotonin Receptor 1E in IF (cc), IF (p). Geeignet für Human.

Kurzübersicht für Serotonin Receptor 1E Antikörper (AA 1-120) (AbBy Fluor® 594) (ABIN2809301)

Target: Serotonin Receptor 1E (HTR1E)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Serotonin Receptor 1E Antikörper ist konjugiert mit AbBy Fluor® 594

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-Serotonin Receptor 1E Antikörper (AbBy Fluor® 594)

Bindungsspezifität: AA 1-120

Homologie: Human,Cow,Pig,Guinea Pig

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human 5HT1E Receptor/SR-1E

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu Serotonin Receptor 1E

Target: Serotonin Receptor 1E (HTR1E)

Andere Bezeichnung: 5HT1E Receptor/SR-1E

Hintergrund:

Synonyms: 5 hydroxytryptamine serotonin receptor 1E, 5 hydroxytryptamine serotonin receptor 1E G protein coupled, 5 hydroxytryptamine 1E receptor, 5-HT-1E, 5-hydroxytryptamine receptor 1E, HTR1E, S31, Serotonin receptor 1E, 5HT1E_HUMAN.

Background: The members of the G-protein-coupled receptor family are distinguished by their slow transmitting response to ligand binding. These seven transmembrane proteins include the adrenergic, serotonin and dopamine receptors. The effect of the signaling molecule can be excitatory or inhibitory depending on the type of receptor to which it binds. b-adrenergic bound to adrenaline activates adenylyl cyclase, while a2-adrenergic receptor bound to adrenaline inhibits adenylyl cyclase. Like the a2-adrenergic receptor, serotonin receptor functions are also mediated by G proteins that inhibit the activity of adenylyl cyclase. The serotonin receptors have been classified into several categories, designated SR-17 (5HT17). Subtypes within the SR-1 group include SR-1A, -1B, -1D, -1E and -1F.

Pathways: JAK-STAT Signalweg, cAMP Metabolic Process