NR1D1 Antikörper (AbBy Fluor® 594)

Produktnummer ABIN2804778

Der Kaninchen Polyklonal Anti-NR1D1-Antikörper wurde für FACS validiert. Er ist geeignet, NR1D1 in Proben von Human, Maus, Ratte und Rind (Kuh) zu detektieren.

Kurzübersicht für NR1D1 Antikörper (AbBy Fluor® 594) (ABIN2804778)

Target: NR1D1 (Nuclear Receptor Subfamily 1, Group D, Member 1 (NR1D1))

Reaktivität: Human, Maus, Ratte, Rind (Kuh)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NR1D1 Antikörper ist konjugiert mit AbBy Fluor® 594

Applikation: Flow Cytometry (FACS)

Produktdetails anti-NR1D1 Antikörper (AbBy Fluor® 594)

Kreuzreaktivität: Rind (Kuh), Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human NR1D1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P)(1:50-200)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu NR1D1

Target: NR1D1 (Nuclear Receptor Subfamily 1, Group D, Member 1 (NR1D1))

Andere Bezeichnung: NR1D1

Hintergrund:

Synonyms: EAR-1, EAR1, ERBA-RELATED 1, hRev, Nr1d1, NR1D1_HUMAN, Nuclear Receptor Rev-ErbA Alpha, Nuclear receptor subfamily 1 group D member 1, Orphan nuclear receptor NR1D1, Rev erbAalpha, Rev erbalpha, Rev-erbA-alpha, Rev-ErbAalpha, REV-ERBalpha, THRA1, THRAL, Thyroid hormone receptor alpha-like, Thyroid hormone receptor, alpha like, V-erbA related protein EAR-1, V-erbA-related protein 1.

Background: NR1D1, a NR1 Thyroid Hormone-Like Receptor, is encoded by the same genomic locus as, but transcribed from the opposite strand of, Thyroid Hormone Receptor Alpha (TR Alpha). NR1D1 is a target of Nuclear Receptor ROR Alpha and a transcription regulator that has been shown to affect myocyte differentiation, adipogenesis, and lipoprotein metabolism. Mice lacking NR1D1 show abnormal postnatal cerebellar development. NR1D1 expression has been documented in human skeletal muscle and a variety of mouse and rat tissues. ESTs have been isolated from human tissue libraries, including cancerous adrenal, blood, brain, breast, colon, duodenum, fetus, head/neck, kidney, lung, skeletal muscle, skin, synovium, uterus, normal brain, breast, colon, eye, heart, pancreas, pituitary, prostate, skeletal muscle, skin, testis and thyroid.

Gen-ID: 9572

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Cellular Response to Molecule of Bacterial Origin, Regulation of Lipid Metabolism by PPARalpha