EPO Antikörper (Center)
Kurzübersicht für EPO Antikörper (Center) (ABIN2799146)
Target
Alle EPO Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 329-357, Center
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Verwendungszweck
- Rabbit Anti-Human EPOR (Center) Antibody
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Immunogen
- This EPOR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 329-357 amino acids from the Central region of human EPOR.
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Isotyp
- Ig Fraction
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Applikationshinweise
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Western Blot, Flow Cytometry, Immunofluorescence
Recommended Dilutions
WB: 1:1000, FC: 1:10-50, IF: 1:10-50EPOR Antibody (Center) . -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.300 mg/mL
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- 2-8°C (short-term), -20°C (long-term)
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- EPO (Erythropoietin (EPO))
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Andere Bezeichnung
- EPO
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Substanzklasse
- Hormone
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Hintergrund
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Target Description: This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants.
Gene Symbol: EPOR
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Molekulargewicht
- 55065 Da
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Gen-ID
- 2057
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UniProt
- P19235
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Pathways
- JAK-STAT Signalweg, Hormone Activity, Negative Regulation of intrinsic apoptotic Signaling, Negative Regulation of Transporter Activity
Target
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