GJA4 Antikörper (C-Term)

Produktnummer ABIN2798870

Produktdetails anti-GJA4 Antikörper

Target: GJA4 (Gap Junction Protein, alpha 4, 37kDa (GJA4))

Bindungsspezifität: AA 303-333, C-Term

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GJA4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Verwendungszweck: Rabbit Anti-Mouse Connexin 37 (C-term) Antibody

Immunogen: This Connexin 37 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 303-333 amino acids from the C-terminal region of human Connexin 37.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Western Blot, Immunohistochemistry
Recommended Dilutions
WB: 1:1000, IHC: 1:10-50GJA4 Antibody (K317).Connexin for immunohistochemistry. Clinical relevance has not been evaluated.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.450 mg/mL

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C (short-term), -20°C (long-term)

Details zu GJA4

Target: GJA4 (Gap Junction Protein, alpha 4, 37kDa (GJA4))

Andere Bezeichnung: Connexin 37 (GJA4 Produkte)

Hintergrund:

Target Description: Gap junctions permit direct cell-to-cell passage of small cytoplasmic molecules, including ions, metabolic intermediates, and second messengers, and thereby mediate intercellular communication. Gap junction channels consist of connexin protein subunits encoded by a multigene family. Erythrokeratodermia variabilis (EKV) is an autosomal dominant disorder of keratinization characterized by migratory erythematous lesions and fixed keratotic plaques. Mutations in the GJB3 gene have been reported in some but not all families, although it has been postulated that the absence of connexin 30.3 can be compensated by other connexins.

Gene Symbol: GJA4

Molekulargewicht: 37414 Da

Gen-ID: 2701

UniProt: P35212

Pathways: Cell-Cell Junction Organization