PCGF2 Antikörper (Center)

Produktnummer ABIN2798813

Der Kaninchen Polyklonal Anti-PCGF2-Antikörper wurde für WB validiert. Er ist geeignet, PCGF2 in Proben von Human zu detektieren.

Kurzübersicht für PCGF2 Antikörper (Center) (ABIN2798813)

Target: PCGF2 (Polycomb Group Ring Finger 2 (PCGF2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PCGF2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PCGF2 Antikörper

Bindungsspezifität: AA 121-150, Center

Verwendungszweck: Rabbit Anti-Human PCGF2 (Center) Antibody

Immunogen: This PCGF2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 121-150 amino acids from the Central region of human PCGF2.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Western Blot
Recommended Dilutions
WB: 1:1000PCGF2 Antibody (Center) .

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.450 mg/mL

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C (short-term), -20°C (long-term)

Details zu PCGF2

Target: PCGF2 (Polycomb Group Ring Finger 2 (PCGF2))

Andere Bezeichnung: PCGF2

Hintergrund:

Target Description: The protein encoded by this gene contains a RING finger motif and is similar to the polycomb group (PcG) gene products. PcG gene products form complexes via protein-protein interaction and maintain the transcription repression of genes involved in embryogenesis, cell cycles, and tumorigenesis. This protein was shown to act as a negative regulator of transcription and has tumor suppressor activity. The expression of this gene was detected in various tumor cells, but is limited in neural organs in normal tissues. Knockout studies in mice suggested that this protein may negatively regulate the expression of different cytokines, chemokines, and chemokine receptors, and thus plays an important role in lymphocyte differentiation and migration, as well as in immune responses.

Gene Symbol: PCGF2

Molekulargewicht: 37788 Da

Gen-ID: 7703

UniProt: P35227

Pathways: Chromatin Binding