Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

Nanog Antikörper (Center)

Dieses Anti-Nanog-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Nanog in WB, IF, IHC und FACS. Geeignet für Human.
Produktnummer ABIN2798793

Kurzübersicht für Nanog Antikörper (Center) (ABIN2798793)

Target

Alle Nanog (NANOG) Antikörper anzeigen
Nanog (NANOG) (Nanog Homeobox (NANOG))

Reaktivität

  • 142
  • 60
  • 24
  • 4
  • 4
  • 4
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
Human

Wirt

  • 131
  • 20
  • 3
  • 1
Kaninchen

Klonalität

  • 121
  • 34
Polyklonal

Konjugat

  • 89
  • 9
  • 7
  • 7
  • 5
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
Dieser Nanog Antikörper ist unkonjugiert

Applikation

  • 116
  • 64
  • 50
  • 45
  • 27
  • 26
  • 26
  • 22
  • 16
  • 15
  • 11
  • 8
  • 5
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC), Flow Cytometry (FACS)
  • Bindungsspezifität

    • 16
    • 16
    • 10
    • 9
    • 9
    • 7
    • 6
    • 6
    • 5
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 94-123, Center

    Verwendungszweck

    Rabbit Anti-Human NANOG (Center) Antibody

    Immunogen

    This NANOG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 94-123 amino acids from the Central region of human NANOG.

    Isotyp

    Ig Fraction
  • Applikationshinweise

    Western Blot, Immunohistochemistry, Immunofluorescence, Flow Cytometry
    Recommended Dilutions
    WB: 1:1000, IHC: 1:10-50, IF: 1:10-50, FC: 1:10-50NANOG Antibody (Center) . FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    2.0 mg/mL

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    2-8°C (short-term), -20°C (long-term)
  • Target

    Nanog (NANOG) (Nanog Homeobox (NANOG))

    Andere Bezeichnung

    NANOG

    Hintergrund

    Target Description: NANOG is a Ttranscription regulator involved in inner cell mass and embryonic stem (ES) cels proliferation and self-renewal. It imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages. This protein blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes. NANOG acts as a transcriptional activator or repressor. It binds optimally to the DNA consensus sequence 5'-[CG][GA][CG]C[GC]ATTAN[GC]-3'. When overexpressed, this protein promotes cells to enter into S phase and proliferation.

    Gene Symbol: NANOG

    Molekulargewicht

    34620 Da

    Gen-ID

    79923

    UniProt

    Q9H9S0

    Pathways

    Stem Cell Maintenance
Sie sind hier:
Chat with us!