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Nanog Antikörper (N-Term)

Der Kaninchen Polyklonal Anti-Nanog-Antikörper wurde für WB, IF, IHC und FACS validiert. Er ist geeignet, Nanog in Proben von Human zu detektieren.
Produktnummer ABIN2798792

Kurzübersicht für Nanog Antikörper (N-Term) (ABIN2798792)

Target

Alle Nanog (NANOG) Antikörper anzeigen
Nanog (NANOG) (Nanog Homeobox (NANOG))

Reaktivität

  • 142
  • 60
  • 24
  • 4
  • 4
  • 4
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
Human

Wirt

  • 131
  • 20
  • 3
  • 1
Kaninchen

Klonalität

  • 121
  • 34
Polyklonal

Konjugat

  • 89
  • 9
  • 7
  • 7
  • 5
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
Dieser Nanog Antikörper ist unkonjugiert

Applikation

  • 116
  • 64
  • 50
  • 45
  • 27
  • 26
  • 26
  • 22
  • 16
  • 15
  • 11
  • 8
  • 5
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC), Flow Cytometry (FACS)
  • Bindungsspezifität

    • 16
    • 16
    • 10
    • 9
    • 9
    • 7
    • 7
    • 5
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 15-49, N-Term

    Verwendungszweck

    Rabbit Anti-Human NANOG (N-term) Antibody

    Immunogen

    This NANOG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 15-49 amino acids from the N-terminal region of human NANOG.

    Isotyp

    Ig Fraction
  • Applikationshinweise

    Western Blot, Immunofluorescence, Immunohistochemistry, Flow Cytometry
    Recommended Dilutions
    WB: 1:1000, IF: 1:10-50, IHC: 1:10-50, FC: 1:10-50Western blot analysis of anti-NANOG Antibody (N-term) . NANOG immunoreactivity is localized to Nucleus significantly.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    2.0 mg/mL

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    2-8°C (short-term), -20°C (long-term)
  • Target

    Nanog (NANOG) (Nanog Homeobox (NANOG))

    Andere Bezeichnung

    NANOG

    Hintergrund

    Target Description: NANOG is a transcription regulator involved in inner cell mass and embryonic stem (ES) cell proliferation and self-renewal. It imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages. This protein blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes. NANOG acts as a transcriptional activator or repressor. It binds optimally to the DNA consensus sequence 5'-[CG][GA][CG]C[GC]ATTAN[GC]-3'. When overexpressed, this protein promotes cells to enter into S phase and proliferation.

    Gene Symbol: NANOG

    Molekulargewicht

    34620 Da

    Gen-ID

    79923

    UniProt

    Q9H9S0

    Pathways

    Stem Cell Maintenance
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