WHSC2 Antikörper (Center)

Produktnummer ABIN2798759

Der Kaninchen Polyklonal Anti-WHSC2-Antikörper wurde für WB validiert. Er ist geeignet, WHSC2 in Proben von Human zu detektieren.

Kurzübersicht für WHSC2 Antikörper (Center) (ABIN2798759)

Target: WHSC2 (Wolf-Hirschhorn Syndrome Candidate 2 (WHSC2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser WHSC2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-WHSC2 Antikörper

Bindungsspezifität: AA 251-279, Center

Verwendungszweck: Rabbit Anti-Human WHSC2 (Center) Antibody

Immunogen: This WHSC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 251-279 amino acids from the Central region of human WHSC2.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Western Blot
Recommended Dilutions
WB: 1:1000WHSC2 Antibody (Center) .

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C (short-term), -20°C (long-term)

Details zu WHSC2

Target: WHSC2 (Wolf-Hirschhorn Syndrome Candidate 2 (WHSC2))

Andere Bezeichnung: WHSC2

Hintergrund:

Target Description: This gene is expressed ubiquitously with higher levels in fetal than in adult tissues. It encodes a protein sharing 93 % sequence identity with the mouse protein. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene is mapped to the 165 kb WHS critical region, and may play a role in the phenotype of the WHS or Pitt-Rogers-Danks syndrome. The encoded protein is found to be capable of reacting with HLA-A2-restricted and tumor-specific cytotoxic T lymphocytes, suggesting a target for use in specific immunotherapy for a large number of cancer patients. This protein has also been shown to be a member of the NELF (negative elongation factor) protein complex that participates in the regulation of RNA polymerase II transcription elongation.

Gene Symbol: NELFA

Molekulargewicht: 57277 Da

Gen-ID: 7469

UniProt: Q9H3P2

Pathways: Chromatin Binding