CD70 Antikörper (Center)

Produktnummer ABIN2798728

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch CD70 in WB und IHC. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für CD70 Antikörper (Center) (ABIN2798728)

Target: CD70 (CD70 Molecule (CD70))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD70 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-CD70 Antikörper

Bindungsspezifität: AA 72-101, Center

Verwendungszweck: Rabbit Anti-Human CD70 (Center) Antibody

Immunogen: This CD70 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 72-101 amino acids from the Central region of human CD70.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Western Blot, Immunohistochemistry
Recommended Dilutions
WB: 1:1000, IHC: 1:10-50CD70 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.500 mg/mL

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C (short-term), -20°C (long-term)

Details zu CD70

Target: CD70 (CD70 Molecule (CD70))

Andere Bezeichnung: CD70

Hintergrund:

Target Description: The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis.

Gene Symbol: CD70

Molekulargewicht: 21118 Da

Gen-ID: 970

UniProt: P32970

Pathways: Cancer Immune Checkpoints