RUNX3 Antikörper (Center)

Produktnummer ABIN2798697

Dieses Anti-RUNX3-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von RUNX3 in WB, IHC und IF. Geeignet für Human.

Kurzübersicht für RUNX3 Antikörper (Center) (ABIN2798697)

Target: RUNX3 (Runt-Related Transcription Factor 3 (RUNX3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RUNX3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-RUNX3 Antikörper

Bindungsspezifität: AA 168-197, Center

Verwendungszweck: Rabbit Anti-Human RUNX3 (Center) Antibody

Immunogen: This RUNX3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 168-197 amino acids from the Central region of human RUNX3.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Western Blot, Immunohistochemistry, Immunofluorescence
Recommended Dilutions
WB: 1:1000, IHC: 1:10-50, IF: 1:10-50Western blot analysis of lysates from HL-60, Jurkat cell line (from left to right), using RUNX3 Antibody (Center) . RUNX3 immunoreactivity is localized to Nucleus and Cytoplasm significantly.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C (short-term), -20°C (long-term)

Details zu RUNX3

Target: RUNX3 (Runt-Related Transcription Factor 3 (RUNX3))

Andere Bezeichnung: RUNX3

Hintergrund:

Target Description: This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Symbol: RUNX3

Molekulargewicht: 44356 Da

Gen-ID: 864

UniProt: Q13761