E2F3 Antikörper (Center)
Kurzübersicht für E2F3 Antikörper (Center) (ABIN2798668)
Target
Alle E2F3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 151-180, Center
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Verwendungszweck
- Rabbit Anti-Human E2F3 (Center) Antibody
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Immunogen
- This E2F3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 151-180 amino acids from the Central region of human E2F3.
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Isotyp
- Ig Fraction
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Applikationshinweise
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Western Blot
Recommended Dilutions
WB: 1:1000E2F3 Antibody (Center) . -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.350 mg/mL
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- 2-8°C (short-term), -20°C (long-term)
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- E2F3
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Hintergrund
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Target Description: The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F1 and E2F2, have an additional cyclin binding domain. This protein binds specifically to retinoblastoma protein pRB in a cell-cycle dependent manner.
Gene Symbol: E2F3
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Molekulargewicht
- 49162 Da
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Gen-ID
- 1871
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UniProt
- O00716
Target
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