CSTB Antikörper (Center)

Produktnummer ABIN2798556

Dieses Anti-CSTB-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von CSTB in WB. Geeignet für Human.

Kurzübersicht für CSTB Antikörper (Center) (ABIN2798556)

Target: CSTB (Cystatin B (Stefin B) (CSTB))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CSTB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CSTB Antikörper

Bindungsspezifität: AA 10-39, Center

Verwendungszweck: Rabbit Anti-Human CSTB (Center) Antibody

Immunogen: This CSTB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 10-39 amino acids from the Central region of human CSTB.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Western Blot
Recommended Dilutions
WB: 1:1000CSTB Antibody (Center) .

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C (short-term), -20°C (long-term)

Details zu CSTB

Target: CSTB (Cystatin B (Stefin B) (CSTB))

Andere Bezeichnung: CSTB

Hintergrund:

Target Description: The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and kininogens. This gene encodes a stefin that functions as an intracellular thiol protease inhibitor. The protein is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. The protein is thought to play a role in protecting against the proteases leaking from lysosomes. Evidence indicates that mutations in this gene are responsible for the primary defects in patients with progressive myoclonic epilepsy (EPM1).

Gene Symbol: CSTB

Molekulargewicht: 11140 Da

Gen-ID: 1476

UniProt: P04080

Pathways: Response to Water Deprivation