CSTB Antikörper

Produktnummer ABIN7260869

Produktdetails anti-CSTB Antikörper

Target: CSTB (Cystatin B (Stefin B) (CSTB))

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CSTB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein of human CSTB (NP_000091.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu CSTB

Target: CSTB (Cystatin B (Stefin B) (CSTB))

Andere Bezeichnung: CSTB (CSTB Produkte)

Synonyme: CST6 antikoerper, EPM1 antikoerper, EPM1A antikoerper, PME antikoerper, STFB antikoerper, ULD antikoerper, CSTB antikoerper, Cyb antikoerper, Epm1 antikoerper, Stfb antikoerper, MGC189005 antikoerper, pme antikoerper, cst6 antikoerper, epm1 antikoerper, stfb antikoerper, AA960480 antikoerper, ARABIDOPSIS THALIANA PHYTOCYSTATIN 6 antikoerper, ATCYS6 antikoerper, ATCYSB antikoerper, cystatin B antikoerper, LOC100008600 antikoerper, LOC100136235 antikoerper, CPI1 antikoerper, cystatin B antikoerper, cystatin B (stefin B) antikoerper, cystatin 14a, tandem duplicate 2 antikoerper, cystatin-B antikoerper, CSTB antikoerper, Cstb antikoerper, cstb antikoerper, cst14a.2 antikoerper, CYSB antikoerper, cpi1 antikoerper, LOC101123265 antikoerper

Hintergrund: The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and kininogens. This gene encodes a stefin that functions as an intracellular thiol protease inhibitor. The protein is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. The protein is thought to play a role in protecting against the proteases leaking from lysosomes. Evidence indicates that mutations in this gene are responsible for the primary defects in patients with progressive myoclonic epilepsy (EPM1). One type of mutation responsible for EPM1 is the expansion in the promoter region of this gene of a CCCCGCCCCGCG repeat from 2-3 copies to 30-78 copies.

Molekulargewicht:

Observed_MW: 14 kDa

Calculated_MW: 11 kDa

Gen-ID: 1476

UniProt: P04080

Pathways: Response to Water Deprivation