PITX2 Antikörper (C-Term)

Produktnummer ABIN2798528

Der Kaninchen Polyklonal Anti-PITX2-Antikörper wurde für WB und IF validiert. Er ist geeignet, PITX2 in Proben von Human zu detektieren.

Kurzübersicht für PITX2 Antikörper (C-Term) (ABIN2798528)

Target: PITX2 (Paired-Like Homeodomain 2 (PITX2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PITX2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-PITX2 Antikörper

Bindungsspezifität: AA 122-151, C-Term

Verwendungszweck: Rabbit Anti-Human PITX2 (C-term) Antibody

Immunogen: This PITX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 122-151 amino acids from the C-terminal region of human PITX2.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Immunofluorescence, Western Blot
Recommended Dilutions
IF: 1:10-50, WB: 1:1000Fluorescent image of Hela cell stained with PITX2 Antibody (C-term) was detected using the purified Pab.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.430 mg/mL

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C (short-term), -20°C (long-term)

Details zu PITX2

Target: PITX2 (Paired-Like Homeodomain 2 (PITX2))

Andere Bezeichnung: PITX2

Hintergrund:

Target Description: Pilx2 is a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. This protein acts as a transcription factor and regulates procollagen lysyl hydroxylase gene expression. It plays a role in the terminal differentiation of somatotroph and lactotroph cell phenotypes, is involved in the development of the eye, tooth and abdominal organs, and acts as a transcriptional regulator involved in basal and hormone-regulated activity of prolactin. Mutations in this protein are associated with Axenfeld-Rieger syndrome, iridogoniodysgenesis syndrome, and sporadic cases of Peters anomaly. A similar protein in other vertebrates is involved in the determination of left-right asymmetry during development.

Gene Symbol: PITX2

Molekulargewicht: 35370 Da

Gen-ID: 5308

UniProt: Q99697

Pathways: Retinoic Acid Receptor Signaling Pathway, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development