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PUMA Antikörper (BH3 Domain)

Name: PUMA Antikörper (BH3 Domain)
SKU: ABIN2798057
Price: 439.56 EUR
Availability: InStock

Der Kaninchen Polyklonal Anti-PUMA-Antikörper wurde für WB, IHC, IF und FACS validiert. Er ist geeignet, PUMA in Proben von Human zu detektieren.

Produktnummer ABIN2798057

Kurzübersicht für PUMA Antikörper (BH3 Domain) (ABIN2798057)

Target

Alle PUMA (BBC3) Antikörper anzeigen

PUMA (BBC3) (BCL2 Binding Component 3 (BBC3))

Reaktivität

Human

Wirt

Kaninchen

Klonalität

Polyklonal

Konjugat

Dieser PUMA Antikörper ist unkonjugiert

Applikation

Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Discover our top product BBC3 Primärantikörper

Bindungsspezifität
16

10

7

7

6

5

4

4

2

2

2

1

1

1

1

1

1

1

1

1
AA 119-154, BH3 Domain

Verwendungszweck

Rabbit Anti-Human Puma BH3 Domain Antibody

Immunogen

This Puma BH3 Domain antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 119-154 amino acids from human Puma BH3 Domain.

Isotyp

Ig Fraction
anti-BCL2 Binding Component 3 (BBC3) (AA 131-180) antibody
BBC3 Reaktivität: Human, Ratte, Schwein WB, ELISA, IP, FACS, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated

anti-BCL2 Binding Component 3 (BBC3) (AA 119-154) antibody
BBC3 Reaktivität: Human WB, IF, FACS, IHC (p) Wirt: Kaninchen Polyclonal RB01353 unconjugated

anti-BCL2 Binding Component 3 (BBC3) (AA 119-154) antibody
BBC3 Reaktivität: Human WB, ELISA, IHC, IF, FACS Wirt: Kaninchen Polyclonal unconjugated

anti-BCL2 Binding Component 3 (BBC3) (BH3 Domain), (C-Term) antibody
BBC3 Reaktivität: Human, Maus WB, IF, FACS, IHC (p), EIA Wirt: Kaninchen Polyclonal unconjugated

anti-BCL2 Binding Component 3 (BBC3) (AA 109-137) antibody
BBC3 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB33714 unconjugated

anti-BCL2 Binding Component 3 (BBC3) (AA 186-199) antibody
BBC3 Reaktivität: Human WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated

anti-BCL2 Binding Component 3 (BBC3) (N-Term) antibody
BBC3 Reaktivität: Human, Maus WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated

anti-BCL2 Binding Component 3 (BBC3) (C-Term) antibody
BBC3 Reaktivität: Human, Maus WB, IHC, ICC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated

anti-BCL2 Binding Component 3 (BBC3) (AA 98-152) antibody
BBC3 Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 5D10 unconjugated

anti-BCL2 Binding Component 3 (BBC3) (AA 2-16) antibody
BBC3 Reaktivität: Human, Ratte, Maus WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated

Applikationshinweise

Western Blot, Immunohistochemistry, Immunofluorescence, Flow Cytometry
Recommended Dilutions
WB: 1:1000, IHC: 1:10-50, IF: 1:10-50, FC: 1:10-50Western blot analysis of anti-Puma BH3 domain Pab .FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

2.000 mg/mL

Lagerung

4 °C,-20 °C

Informationen zur Lagerung

2-8°C (short-term), -20°C (long-term)
Target

PUMA (BBC3) (BCL2 Binding Component 3 (BBC3))

Andere Bezeichnung

Puma

Hintergrund

Target Description: PUMA is one of the pro-apoptotic Bcl-2 family members including Bax and Noxa, which are also transcriptional targets of p53. The PUMA gene encodes two BH3 domain-containing proteins termed PUMA-a and PUMA-b. PUMA proteins bind Bcl-2, localize to the mitochondria, and induce cytochrome c release and apoptosis in response to p53. PUMA may be a direct mediator of p53-induced apoptosis.
Gene Symbol: BBC3

Molekulargewicht

20532 Da

Gen-ID

27113

UniProt

Q9BXH1

Pathways

p53 Signalweg, Positive Regulation of Endopeptidase Activity