KREMEN2 Antikörper (Center)
Kurzübersicht für KREMEN2 Antikörper (Center) (ABIN2798011)
Target
Alle KREMEN2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 248-276, Center
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Verwendungszweck
- Rabbit Anti-Human KREMEN2 (Center) Antibody
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Immunogen
- This KREMEN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 248-276 amino acids from the Central region of human KREMEN2.
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Isotyp
- Ig Fraction
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Applikationshinweise
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Western Blot
Recommended Dilutions
WB: 1:1000KREMEN2 Antibody (Center) . -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.5 mg/mL
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- 2-8°C (short-term), -20°C (long-term)
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- KREMEN2 (Kringle Containing Transmembrane Protein 2 (KREMEN2))
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Andere Bezeichnung
- KREMEN2
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Hintergrund
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Target Description: This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein forms a ternary membrane complex with DKK1 and the WNT receptor lipoprotein receptor-related protein 6 (LRP6), and induces rapid endocytosis and removal of LRP6 from the plasma membrane. It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene.
Gene Symbol: KREMEN2
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Molekulargewicht
- 48849 Da
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Gen-ID
- 79412
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UniProt
- Q8NCW0
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Pathways
- WNT Signalweg
Target
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