PAI1 Antikörper (Center)

Produktnummer ABIN2797962

Dieses Anti-PAI1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von PAI1 in WB und FACS. Geeignet für Human.

Kurzübersicht für PAI1 Antikörper (Center) (ABIN2797962)

Target: PAI1 (SERPINE1) (Plasminogen Activator Inhibitor 1 (SERPINE1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PAI1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS)

Produktdetails anti-PAI1 Antikörper

Bindungsspezifität: AA 188-216, Center

Verwendungszweck: Rabbit Anti-Human SERPINE1 (Center) Antibody

Immunogen: This SERPINE1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 188-216 amino acids from the Central region of human SERPINE1.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Western Blot, Flow Cytometry
Recommended Dilutions
WB: 1:1000, FC: 1:10-50Western blot analysis of SERPINE1 (arrow) using rabbit polyclonal SERPINE1 Antibody (Center) .FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C (short-term), -20°C (long-term)

Details zu PAI1

Target: PAI1 (SERPINE1) (Plasminogen Activator Inhibitor 1 (SERPINE1))

Andere Bezeichnung: SERPINE1

Hintergrund:

Target Description: This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene Symbol: SERPINE1

Molekulargewicht: 45060 Da

Gen-ID: 5054

UniProt: P05121

Pathways: p53 Signalweg, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Autophagie, Smooth Muscle Cell Migration