CCR8 Antikörper (C-Term)

Produktnummer ABIN2797017

Dieses Anti-CCR8-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von CCR8 in WB und FACS. Geeignet für Human.

Kurzübersicht für CCR8 Antikörper (C-Term) (ABIN2797017)

Target: CCR8 (Chemokine (C-C Motif) Receptor 8 (CCR8))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CCR8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS)

Produktdetails anti-CCR8 Antikörper

Bindungsspezifität: AA 290-317, C-Term

Verwendungszweck: Rabbit Anti-Human CCR8 (C-term) Antibody

Immunogen: This CCR8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 290-317 amino acids from the C-terminal region of human CCR8.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Western Blot, Flow Cytometry
Recommended Dilutions
WB: 1:1000, FC: 1:10-50CCR8 Antibody (C-term) .FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C (short-term), -20°C (long-term)

Details zu CCR8

Target: CCR8 (Chemokine (C-C Motif) Receptor 8 (CCR8))

Andere Bezeichnung: CCR8

Hintergrund:

Target Description: CCR8 encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. I-309, thymus activation-regulated cytokine (TARC) and macrophage inflammatory protein-1 beta (MIP-1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. CCR8 is located at the chemokine receptor gene cluster region.

Gene Symbol: CCR8

Molekulargewicht: 40844 Da

Gen-ID: 1237

UniProt: P51685