Phospholamban Antikörper (pThr17)

Produktnummer ABIN2794308

Dieses Anti-Phospholamban-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Phospholamban in DB. Geeignet für Human.

Kurzübersicht für Phospholamban Antikörper (pThr17) (ABIN2794308)

Target: Phospholamban (PLN)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Phospholamban Antikörper ist unkonjugiert

Applikation: Dot Blot (DB)

Produktdetails anti-Phospholamban Antikörper

Bindungsspezifität: pThr17

Verwendungszweck: Rabbit Anti-Human Phospho-PLB(T17) Antibody

Immunogen: This PLB Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T17 of human PLB.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Dot Blot
Recommended Dilutions
DB: 1:500
Dot blot analysis of anti-Phospho-PLB-T17 Phospho-specific Pab on nitrocellulose membrane. 50 ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5 μg per ml.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C (short-term), -20°C (long-term)

Details zu Phospholamban

Target: Phospholamban (PLN)

Andere Bezeichnung: PLB

Hintergrund:

Target Description: Phospholamban (PLB) is a 52 amino acid phosphoprotein which regulates the calcium pump of cardiac sarcoplasmic reticulum (SR). PLB is an oligomer of five identical subunits each having a cytoplasmic and transmembrane domain. The cytoplasmic domain (residues 1 to 25) contains the phosphorylation sites and is highly basic and readily cleaved by proteases, whereas the transmembrane domain (residues 25 to 52) is mostly hydrophobic, protease resistant and stabilizes the pentamer.

Gene Symbol: PLN

Molekulargewicht: 6109 Da

Gen-ID: 5350

UniProt: P26678

Pathways: Negative Regulation of Transporter Activity