DGKA Antikörper (C-Term)

Produktnummer ABIN2793354

Dieses Anti-DGKA-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von DGKA in WB und IHC. Geeignet für Human.

Kurzübersicht für DGKA Antikörper (C-Term) (ABIN2793354)

Target: DGKA (Diacylglycerol Kinase, alpha 80kDa (DGKA))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DGKA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-DGKA Antikörper

Bindungsspezifität: AA 598-628, C-Term

Verwendungszweck: Rabbit Anti-Human DGKA (C-term) Antibody

Immunogen: This DGKA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 598-628 amino acids from the C-terminal region of human DGKA.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Western Blot, Immunohistochemistry
Recommended Dilutions
WB: 1:1000, IHC: 1:50-100Western blot analysis of anti-DGKA Antibody (C-term) was detected using the purified Pab.
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry, clinical relevance has not been evaluated. BC = breast carcinoma, HC = hepatocarcinoma.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 2.0 mg/mL

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C (short-term), -20°C (long-term)

Details zu DGKA

Target: DGKA (Diacylglycerol Kinase, alpha 80kDa (DGKA))

Andere Bezeichnung: DGKA

Hintergrund:

Target Description: Upon cell stimulation, the kinase DGKA converts the second messenger diacylglycerol into phophatidate, initiating the resynthesis of phosphatidylinositols and attenuating protein kinase C activity. DGKA is stimulated by calcium and phosphatidylserine, and is phosphorylated by protein kinase C. Tissue expression is in lymphocytes and oligodengroglial cells. DGKA contains 2 zinc-dependent phorbol-ester and DAG binding domains, and 2 EF-hand calcium binding domains.

Gene Symbol: DGKA

Molekulargewicht: 82630 Da

Gen-ID: 1606

UniProt: P23743